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Transplantation Drug Development Pipeline Review, 2017
Summary
This report provides an overview of the transplantation pipeline landscape, specifically covering drugs used to prevent and treat organ rejection and graft-versus-host disease. The report provides comprehensive information on the therapeutics under development and key players involved in therapeutic development for graft-versus-host disease (GVHD), and the rejection of bone, liver, kidney, lung and heart transplants.
Transplant rejection is a complication that can occur after the replacement of a defective host organ with a foreign donor organ. General risks associated with transplantation are bleeding, infection, clots, and cardiovascular disorders. Additionally, following a transplant, the immune system may consider the transplanted heart as foreign and mount a response against it, especially if the antigens expressed by the tissues in each do not match. Generally, immunosuppressive drugs are administered simultaneously with the transplant in order to minimize this risk. These immunosuppressive drugs prevent the body from either identifying or attacking the foreign organ via various immune responses thus blocking organ rejection and facilitating a successful transplant.
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The size of these pipelines ranges from seven products in heart transplantation to 121 in bone marrow transplantation. A wide range of targets, including integrins, chemokine receptors, protein kinases and cadherins are being developed, with no particular class of target predominating in terms of pipeline volume within each indication. However, there is a clear trend towards immune system molecular targets being studied, reflecting the underlying immune-based pathophysiology of these indications.
Scope
- Which companies are the most active within the pipeline for transplantation therapeutics?
- Which pharmaceutical approaches are the most prominent at each stage of the pipeline and within each indication?
- To what extent do universities and institutions play a role within this pipeline, compared to pharmaceutical companies?
- What are the most important R&D milestones and data publications to have happened in the field of transplantation therapeutics?
Reasons to buy
- Understand the overall pipeline, with an at-a-glance overview of all products in therapeutic development for each indication
- Assess the products in development in granular detail, with an up-to-date overview of each individual pipeline program in each indication, and a comprehensive picture of recent updates and milestones for each
- Analyze the companies, institutions and universities currently operating in the pipeline, and the products being fielded by each of these
- Understand the composition of the pipeline in terms of molecule type, molecular target, mechanism of action and route of administration
Make an Enquiry about TOC @ https://www.researchmoz.us/transplantation-drug-development-pipeline-review-2017-report.html/toc
Table of Contents
GBI Research Report Guidance 2
Executive Summary 3
Table of Contents 4
List of Tables 6
List of Figures 12
Introduction 14
Transplantation Report Coverage 14
Bone Marrow Transplant Rejection - Overview 14
Graft Versus Host Disease (GVHD) - Overview 14
Liver Transplant Rejection - Overview 14
Kidney Transplant Rejection - Overview 14
Lung Transplant Rejection - Overview 14
Heart Transplant Rejection - Overview 15
Therapeutics Development 16
Bone Marrow Transplant Rejection 16
Graft Versus Host Disease (GVHD) 27
Liver Transplant Rejection 38
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Transplantation Drug Development Pipeline Review, 2017
Summary
This report provides an overview of the transplantation pipeline landscape, specifically covering drugs used to prevent and treat organ rejection and graft-versus-host disease. The report provides comprehensive information on the therapeutics under development and key players involved in therapeutic development for graft-versus-host disease (GVHD), and the rejection of bone, liver, kidney, lung and heart transplants.
Transplant rejection is a complication that can occur after the replacement of a defective host organ with a foreign donor organ. General risks associated with transplantation are bleeding, infection, clots, and cardiovascular disorders. Additionally, following a transplant, the immune system may consider the transplanted heart as foreign and mount a response against it, especially if the antigens expressed by the tissues in each do not match. Generally, immunosuppressive drugs are administered simultaneously with the transplant in order to minimize this risk. These immunosuppressive drugs prevent the body from either identifying or attacking the foreign organ via various immune responses thus blocking organ rejection and facilitating a successful transplant.
To Get Sample Copy of Report visit @ https://www.researchmoz.us/enquiry.php?type=S&repid=1217019
The size of these pipelines ranges from seven products in heart transplantation to 121 in bone marrow transplantation. A wide range of targets, including integrins, chemokine receptors, protein kinases and cadherins are being developed, with no particular class of target predominating in terms of pipeline volume within each indication. However, there is a clear trend towards immune system molecular targets being studied, reflecting the underlying immune-based pathophysiology of these indications.
Scope
- Which companies are the most active within the pipeline for transplantation therapeutics?
- Which pharmaceutical approaches are the most prominent at each stage of the pipeline and within each indication?
- To what extent do universities and institutions play a role within this pipeline, compared to pharmaceutical companies?
- What are the most important R&D milestones and data publications to have happened in the field of transplantation therapeutics?
Reasons to buy
- Understand the overall pipeline, with an at-a-glance overview of all products in therapeutic development for each indication
- Assess the products in development in granular detail, with an up-to-date overview of each individual pipeline program in each indication, and a comprehensive picture of recent updates and milestones for each
- Analyze the companies, institutions and universities currently operating in the pipeline, and the products being fielded by each of these
- Understand the composition of the pipeline in terms of molecule type, molecular target, mechanism of action and route of administration
Make an Enquiry about TOC @ https://www.researchmoz.us/transplantation-drug-development-pipeline-review-2017-report.html/toc
Table of Contents
GBI Research Report Guidance 2
Executive Summary 3
Table of Contents 4
List of Tables 6
List of Figures 12
Introduction 14
Transplantation Report Coverage 14
Bone Marrow Transplant Rejection - Overview 14
Graft Versus Host Disease (GVHD) - Overview 14
Liver Transplant Rejection - Overview 14
Kidney Transplant Rejection - Overview 14
Lung Transplant Rejection - Overview 14
Heart Transplant Rejection - Overview 15
Therapeutics Development 16
Bone Marrow Transplant Rejection 16
Graft Versus Host Disease (GVHD) 27
Liver Transplant Rejection 38
About ResearchMoz
ResearchMoz is the one stop online destination to find and buy market research reports & Industry Analysis. We fulfill all your research needs spanning across industry verticals with our huge collection of market research reports. We provide our services to all sizes of organizations and across all industry verticals and markets. Our Research Coordinators have in-depth knowledge of reports as well as publishers and will assist you in making an informed decision by giving you unbiased and deep insights on which reports will satisfy your needs at the best price.
For More Information Kindly Contact:
ResearchMoz
Mr. Nachiket Ghumare,
Tel: +1-518-621-2074
USA-Canada Toll Free: 866-997-4948
Email: sales@researchmoz.us
Follow us on LinkedIn @ http://bit.ly/1TBmnVG
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